Prof. Dr. Deniz Tasdemir

Head of Research Unit Marine Natural Products Chemistry

Director of GEOMAR-Biotech: GEOMAR Centre for Marine Biotechnology 

Office:
Room: 15
Phone: +49 431 600-4430
Fax: ++49 431 600-4441
E-Mail: dtasdemir(at)geomar.de

Personal Assistant / Office Management:
Bettina Reuter
Phone: ++49-431 600-4437
Fax: ++49-431 - 600-4441
E-Mail: breuter(at)geomar.de

Address:
RU Marine Natural Products Chemistry
GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech)
Am Kiel-Kanal 44 | 24106 Kiel | Germany

Education and Career Stages

- Full Professor of Marine Natural Products Chemistry at GEOMAR, since August 2014

- Full Professor of Marine Biodiscovery, National University of Ireland Galway, School of Chemistry, Ireland, 2011

- Senior lecturer at London School of Pharmacy (now UCL School of Pharmacy), UK, 2006

- Dr. Helmut Legerlotz Fellow, University of Zurich, Institute of Organic Chemistry, Switzerland, 2002

- Post-doctoral fellow, University of Utah, College of Pharmacy, USA, 1998-2001

- Assistant Professor, Hacettepe University, Ankara, Turkey, 1998

- PhD (Hons) at ETH Zurich, Department of Pharmacy, Switzerland, 1997

- MSc (Hons) in Pharmacognosy, Hacettepe University, Turkey

- BSc (Hons) in Pharmacy, Hacettepe University, Ankara, Turkey

Distinctions and Awards

- Waters Award for Excellence in Natural Products Innovation, 2016

- Egon Stahl Silver Medal of Society for Medicinal Plant Research (GA), 2005

- Pierre Fabre Prize of the Phytochemical Society of Europe (PSE), 2004

- ETH-Zurich Medal, Distinction for PhD Thesis, 1997

- Science Motivation Award and Ihsan Dogramacı Award for Excellent Success in Education: Graduation with the highest honors at Faculty of Pharmacy, Hacettepe University

Editorial Functions

- Member of the Editorial Board of Marine Drugs

- Member of the Advisory Editorial Board of Planta Medica

- Member of the Editorial Board of Phytochemistry Letters

- Member of the Editorial Board of Frontiers in Ethnopharmacology

- Guest Editor, Marine Drugs, Special issue: Antiprotozoal Marine Natural Products, Nov. 2013

(http://www.mdpi.com/journal/marinedrugs/special_issues/antiprotozoal_marine

- Guest Editor, Journal of Natural Products, Special issue in honor of Professor Otto Sticher (with M. Hamburger and J. Orjala, vol.77, issue 3, March 2014)

- Guest Editor, Planta Medica, Special issue in Marine Natural Products, vol. 82, issues 9/10, June 2016)

Functions in Learned Natural Product Societies

- Member of the Advisory Board of Society for Medicinal Plant and Natural Product Research (GA). Since 2009 -

- Member of the Permanent Committee of Young Researchers Workshop, Society for Medicinal Plant and Natural Product Research (GA). 2009 - 2015

- Membership secretary of the Phytochemical Society of Europe (PSE). 2008- 2013

Selected Publications

Parrot, D., Papazian, S., Foil, D., Tasdemir D. Imaging the unimaginable: Desorption Electrospray Ionization - Imaging Mass Spectrometry (DESI-IMS) in natural product research. Planta Medica, 2018, doi: 10.1055/s-0044-100188.

Chianese, G., Silber J., Luciano, P., Merten C., Erpenbeck, D., Topaloglu B., Kaiser M., Tasdemir D. Antiprotozoal linear furanosesterterpenoids from the marine sponge Ircinia oros. Journal of Natural Products, 2017, 80, 2566-2571, doi: 10.1021/acs.jnatprod.7b00543.

Smyrniotopoulos, V., Merten, C., Kaiser, M., Tasdemir, D. Bifurcatriol, an Antiprotozoal Acyclic Diterpene from the Brown Alga Bifurcaria bifurcata. Marine Drugs, 2017, 15, 245, doi:10.3390/md15080245

Silber, J., Kramer, A., Labes, A., Tasdemir, D. From Discovery to Production: Biotechnology of Marine Fungi for the Production of New Antibiotics. Marine Drugs, 2016, 14(7), 137. doi:10.3390/md14070137

Merten, C., Smyrniotopoulos, V., Tasdemir, D. Assignment of absolute configurations of highly flexible linear diterpenes from the brown alga Bifurcaria bifurcata by VCD spectroscopy. Chemical Communications, 2015, 51, 16217-16220.

Fernández, A., Grienke, U., Soler-Vila, A., Guihéneuf, F., Stengel, D., Tasdemir, D. Seasonal and geographical variations in the biochemical composition of the blue mussel (Mytilus edulis L.) from Ireland. Food Chemistry, 2015, 177, 43-52.

Smyrniotopoulos, V., Rae, M., Soldatou, S., Ding, Y., Wolff, C., McCormack, C., Coleman, C.M., Ferreira, D., Tasdemir, D. Sulfated steroid - amino acid conjugates from the Irish marine sponge Polymastia boletiformis. Marine Drugs, 2015, 13, 1632-1646.

Grienke, U., Silke, J., Tasdemir, D. Bioactive compounds from marine mussels and their effects on human health. Food Chemistry, 2014, 142, 48-60.

Carballeira, N.M., Bwalya, A.G., Itoe, M.A., Andricopulo, A.D., Cordero-Maldonado, M.L., Kaiser, M., Mota, M.M., Crawford, A.D., Guido, R.V.C., Tasdemir, D. 2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes. Bioorganic & Medicinal Chemistry Letters, 2014, 24, 4151-4157.

Chianese, G., Scala, F., Calcinai, B., Cerrano, C., Dien, H.A., Kaiser, M. Tasdemir, D., Taglialatela-Scafati, O. Natural and semi-synthetic analogues of manadoperoxide B reveal new structural requirements for trypanocidal activity. Marine Drugs, 2013, 11, 3297-3308.

Spavieri, J., Allmendinger, A., Kaiser, M., Itoe, M.A., Blunden, G., Mota, M.M., Tasdemir, D. Assessment of dual life stage antiplasmodial activity of British seaweeds. Marine Drugs, 2013, 11, 4019-4034.

Chianese, G., Fattorusso, E., Scala, F., Teta, R., Calcinai, B., Bavestrello, G., Dien, H.A., Kaiser, M., Tasdemir, D., Taglialatela-Scafati, O. Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin. Organic & Biomolecular Chemistry, 2012, 10, 7197-7207.

Fitzgerald, C., Gallagher, E., Tasdemir, D., Hayes, M. Heart health peptides from macroalgae and their potential use in functional foods. Journal of Agricultural and Food Chemistry, 2011, 59, 6829-6836.

Regalado, E.L., Tasdemir, D., Kaiser, M., Cachet, N., Amade, P., Thomas, O.P. Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium. Journal of Natural Products, 2010, 73, 1404-1410.

Scala, F., Fattorusso, E., Menna, M., Taglialatela-Scafati, O., Tierney, M., Kaiser, M., Tasdemir, D.  Bromopyrrole alkaloids as lead compounds against protozoan parasites, Marine Drugs, 2010, 8, 2162-2174.

Giddens, A.C., Neilsen, L., Boshoff, H.I., Tasdemir, D., Perozzo, R., Kaiser, M., Wang, F., Sacchettini, J.C., Copp, B.R. Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities. Tetrahedron, 2008, 64, 1242-1249.

Sertan, A.A., Predicala, R.Z., Bernardo, E.B., Neilan, B.A., Elardo, S.P., Mangalindan, G.C., Tasdemir, D., Ireland, C.M., Barraquio, W.L., Concepcion, G.P. Pseudovibrio denitrificans strain Z143-1, a heptyl prodigiosin-producing bacterium isolated from a Philippine tunicate. FEMS Microbiology Letters, 2007, 277, 188-196.

Tasdemir, D., Topaloglu, B., Perozzo, R., Brun, R., O’Neill, R., Carballeira, N.M., Zhang, X., Tonge, P.J., Linden, A., Rüedi, P. Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli. Bioorganic & Medicinal Chemistry, 2007, 15, 6834-6845 

Davis, R.A., Mangalindan, G.C., Bojo, Z.P., Antemano, R.R., Rodriguez, N.O., Concepción, G.P., Samson, S.C., de Guzman, D., Cruz, L.J., Tasdemir, D., Harper, M.K., Feng, X., Carter, G.T., Ireland C.M. Microcionamides A and B, Bioactive Peptides from the Philippine Sponge Clathria (Thalysias) abietina. Journal of Organic Chemistry, 2004, 69, 4170-4176.

Marshall, K.M., Matsumoto, S.S., Holden, J.A., Concepcion, G.P., Tasdemir, D., Ireland, C.M., Barrows, L.R. The Anti-neoplastic and Novel Topoisomerase II Mediated Cytotoxicity of Neoamphimedine, a Marine Pyridoacridine. Biochemical Pharmacology, 2003, 66, 447-458.

Tasdemir, D., Mallon, R., Greenstein, M., Feldberg, L.R., Kim, S.C., Collins, K., Wojciechowicz, D., Mangalindan, G.C., Concepción, G.P., Harper, M.K., Ireland, C.M. Aldisine Alkaloids from the Philippine Sponge Stylissa massa are Potent Inhibitors of Mitogen-Activated Protein Kinase Kinase-1 (MEK-1). Journal of Medicinal Chemistry, 2002, 45, 529-532.

Tasdemir, D., Marshall, K.M., Mangalindan, G.C., Concepción, G.P., Barrows, L.R., Harper, M.K., Ireland, C.M. Deoxyamphimedine, a new pyridoacridine alkaloid from two tropical Xestospongia sponges. Journal of Organic Chemistry, 2001, 66, 3246-3248.