Dr. Larissa Buedenbender

Research Division 3: Marine Ecology
RU Marine Natural Products Chemistry

Office:
Room: 023
Phone: +49 431 600-4424
Fax: +49 431 600-4441
E-Mail: lbuedenbender(at)geomar.de

Address:
Am Kiel-Kanal 44
D-24106 Kiel

Research interests

I am interested in implementing interdisciplinary approaches that connect analytical chemistry, microbial and molecular biology, metabolomics and bioinformatics in order to study the microbial diversity associated with marine organisms and the potential of their secondary metabolome for application in drug discovery and biotechnology.

Academic positions

Postdoctoral researcher in Marine Natural Products Chemistry at GEOMAR, Kiel, Germany, since May 2018

Tutor and Laboratory demonstrator for undergraduate Chemistry, School of Environment and Science, Griffith University, Australia, 2013 – 2018

PhD in Marine Microbial Natural Products, Environmental Futures Research Institute, Griffith University, Australia, 2014 – 2018

Publications

Buedenbender, L., Robertson, L.P., Lucantoni, L., Avery, V.M., Kurtböke, D. İ., Carroll, A.R., HSQC-TOCSY Fingerprinting-Directed Discovery of Antiplasmodial Polyketides from the Marine Ascidian-Derived Streptomyces sp. (USC-16018), Marine Drugs, 2018, 16(6), 189; DOI: 10.3390/md16060189

Buedenbender, L., Carroll, A.R., Kurtböke, D. İ., Integrated approaches in marine actinomycete biodiscovery, In: Frontiers in Clinical Drug Research - Anti Infectives, 2018, (accepted).

Buedenbender, L., Habener, L.J., Grkovic, T., Kurtböke, D. İ., Duffy, S., Avery, V.M., Carroll, A.R., HSQC-TOCSY fingerprinting for prioritization of polyketide and peptide producing microbial isolates, Journal of Natural Products, 2018, 81(4): 957-965; DOI: 10.1021/acs.jnatprod.7b01063

Buedenbender, L., Carroll, A.R.,Ekins, M., Kurtböke, D. İ., Diversity and chemical potential of actinomycetes associated with three Australian ascidians, Diversity, 2017, 9(4), 53; DOI: 10.3390/d9040053.

Buedenbender, L., Grkovic, T., Duffy, S., Kurtböke, D. İ., Avery, V.M., Carroll, A.R., Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp., Tetrahedron Letters, 2016, 57(52): 5893-5895.

Selected presentations

Buedenbender, L., Wenzel-Storjohann, A., Tasdemir, D. „Bioactivity mapping of a SPE fractionated Fucus vesiculosus extract using LC-MS/MS based metabolomics”, Poster and oral presentation at BIOPROSP_19 - The 9th International Conference on Marine Biotechnology, Tromsø, Norway, 02/2019

Buedenbender, L., Habener, L.J., Grkovic, T., Kurtböke, D. İ., Duffy, S., Avery, V.M., Carroll, A.R., “HSQC-TOCSY NMR profiling: making informed microbial strain selection for natural product discovery”, oral presentation at the 13th International Conference of the Metabolomics Society, Brisbane, Australia, 06/2017.

Buedenbender, L., Grkovic, T., Kurtböke, D. İ., Carroll, A.R., “Systematic HSQC-TOCSY profiling of ascidian-associated actinomycete extracts to aid strain selection for natural product discovery”, oral presentation at the 10th International Symposium for Marine Natural Products, Fortaleza, Brazil, 09/2016.

Buedenbender, L., Grkovic, T., Kurtböke, D. İ., Carroll, A.R., “Integrated high-throughput profiling of ascidian derived actinomycete extracts to aid strain selection for natural product discovery”, oral presentation at 1st ANZ Marine Biotechnology Society Symposium, Adelaide, Australia, 03/2016

Buedenbender, L., Grkovic, T., Duffy, S., Kurtböke, D. İ., Avery, V.M., Carroll, A.R., “Naseseazine C, a new dimeric diketopiperizine from a marine sediment derived Streptomyces sp.”, oral presentation at RACI natural products chemistry symposium, Sydney, Australia, 10/2015

Buedenbender, L., “Marine actinomycete natural product biodiscovery”, oral presentation at EFRI student symposium, Brisbane, 09/2015