Marine Natural Products Chemistry
Marine natural products (MNPs) are prolific source of many life-saving drugs and functional ingredients. The research unit Marine Natural Product Chemistry deals with all aspects of marine biotechnology and marine biodiscovery using the enormous biological diversity of marine macro- and microorganisms to identify novel molecules. This includes the cultivation, extraction, biological activity screening, chemical profiling and dereplication of marine extracts followed by purification, 3D structure elucidation and identification of mechanism of biological/ecological activity of marine secondary metabolites.
Our main research interests include natural product drug discovery and chemical ecology of marine metabolites through marine metabolomics coupled with imaging techniques. For these purposes, we use modern fermentation, hyphenated chromatographic techniques as well as high-resolution spectroscopic and mass-spectrometry-based imaging techniques available in-house. The use of the emerging techniques (e.g. omics, imaging, chemical fingerprinting / profiling) and available infrastructure also enables us to rapidly profile and monitor the production of key marine constituents under ecological challenges, such as diseases, global warming, pollution or invasive character.
GEOMAR Centre for Marine Biotechnology GEOMAR-Biotech, a state-of-the-art research centre carrying out both basic and applied research, is part of the research unit Marine Natural Product Chemistry.
Photos: GEOMAR, Leila Ivarsson, Christoph Wirth
Head of the Research Unit:
Prof. Dr. Deniz Tasdemir
GEOMAR Helmholtz Centre for Ocean Research Kiel
Phone: +49-431 600-4430
Fax: +49-431 600-4441
Am Kiel-Kanal 44
Personal Assistant / Office Management:
Phone: ++49-431 600-4437
Fax: ++49-431 - 600-4441