Topic 6: Marine and polar Life

RD 3: Marine Ecology
RU Marine Natural Products Chemistry

Office:
Building 5 (ENB), Room: 2.419
Phone: +49 431 600-1217
Email: selsayed(at)geomar.de

Address:
RU Marine Natural Products Chemistry
GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech)
Wischhofstrasse 1-3 | 24148 Kiel | Germany

Research interests:

Marine Natural Products Chemistry, Fungal Secondary Metabolites, Fermentation, Extraction, Purification, Chemical and Biological Characterization via spectroscopic analyses such as UV, IR, 1D/2D NMR and HRMS

Projects:

KardioMarin - Cardiological Therapy with Marine Active Ingredients

Duration: 2026 - 2028

Academic positions:

Since 10.2026: Postdoctoral researcher at GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech) Kiel.

07.2022 - 06.2024: Georg-Forster Fellowship for Experienced Researchers funded by the Alexander von Humboldt (AvH) Foundation at the Helmholtz Centre for Infection, Braunschweig, Germany.

12.2021 - Present: Professor, Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

01.2007 - 12.2010: Ph.D. “Dr. rer. nat.” in Pharmaceutical Biology at Heinrich Heine University Duesseldorf, Germany.

05.2002 - 06.2006: Master in Pharmaceutical Sciences (Pharmacognosy), Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

05.1995 - 05.2000: Bachelor in Pharmaceutical Sciences at Faculty of pharmacy, Ain Shams University, Cairo, Egypt.

Selected Publications:

Zhu L, Hernández-Restrepo M, Agudelo-Restrepo M, Ibrahim MAA, Charria-Girón E, Ebada SS, Marin-Felix Y. Bioactive eremophilane meroterpenoids produced by the soil fungus Stchigelomyces brunnescens gen. et comb. nov. Mycology. 2026; 1–22. doi.org/10.1080/21501203.2026.2616893

Agudelo-Restrepo M, Hernández-Restrepo M, Ibrahim MAA, Charria-Girón E, Ebada SS, Marin-Felix Y. New sordarialean lineage Garciamycella chlamydospora (Sordariales, Schizotheciaceae) produces rare antifungal papulacandins. IMA Fungus. 2026; 17:e177411. doi.org/10.3897/imafungus.17.177411

Wennrich JP, Holzenkamp C, Fushimi S, Ibrahim MAA, Ashrafi S, Maier W, Schrey H, Ebada SS, Stadler M. (2025). Cordypyridones E–J: Antibiofilm 2-pyridone alkaloids from the nematode antagonistic fungus Laburnicola nematophila. Journal of Natural Products. 2025; 88:2406–2415. doi/10.1021/acs.jnatprod.5c00768

Valencia-Revelo D, Charria-Girón E, Schmidt K, Reinecke S, Vasco-Palacios AM, Stradal T, Marin-Felix Y, Caicedo-Ortega NH, Ebada SS. Unconventional semi-solid cultivation enhances cytochalasins production by the Colombian fungus Xylaria sp. CM-UDEA-H199. BMC Biotechnology. 2025; 25:57. doi.org/10.1186/s12896-025-00978-2

Wennrich JP, Ebada SS, Sepanian E, Holzenkamp C, Khalid SJ, Schrey H, Maier W, Kurtán T, Ashrafi S, Stadler M. Omnipolyphilins A and B: novel chlorinated cyclotetrapeptides and naphtho-α-pyranones from two plant nematode-derived fungi Polyphilus sieberi. Journal of Agricultural and Food Chemistry. 2024; 72:6998–7009. https://doi.org/10.1021/acs.jafc.4c00572

Pripdeevech P, Khruengsai S, Tanapichatsakul C, Afifi WM, Sum WC, Hyde KD, Ebada SS. Cytotoxic Polyhydroxy-Isoprenoids from Neodidymelliopsis negundinis. Journal of Natural Products. 2024; 87:349-357. doi.org/10.1021/acs.jnatprod.3c01094

Sum WC, , Kirchenwitz M, Wanga L, Decock C, Stradal TEB, Matasyoh JC, Mándi A, Kurtán T, . Neurite outgrowth-inducing Drimane-type Sesquiterpenoids Isolated from Cultures of the Polypore Abundisporus violaceus MUCL 56355. Journal Natural Products. 2023; 86:2457-2467. doi.org/10.1021/acs.jnatprod.3c00525

Sum WC, , Kirchenwitz M, Kellner H, , Stradal TEB, Matasyoh JC, . Hericioic Acids A-G and Hericiofuranoic Acid, Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum. Journal of Agricultural and Food Chemistry. 2023; 71(29): 11094-11103. doi.org/10.1021/acs.jafc.3c02897