Prof. Dr. Deniz Tasdemir

Leiterin der Forschungseinheit Marine Naturstoffchemie

Direktorin des GEOMAR-Biotech: GEOMAR Zentrum für Marine Biotechnologie

Raum: 2.426
Tel.: +49-431 600-4430
E-Mail: dtasdemir(at)

Julia Chapela Collazo
Tel.: +49-431 600-4437
E-Mail: jchapelacollazo(at)

FE Marine Naturstoffchemie
GEOMAR Zentrum für Marine Biotechnologie (GEOMAR-Biotech)
Wischhofstrasse 1-3 | 24148 Kiel | Germany

Education and Career Stages

  • Full Professor of Marine Natural Products Chemistry at GEOMAR, since August 2014
  • Full Professor of Marine Biodiscovery, National University of Ireland Galway, School of Chemistry, Ireland, 2011
  • Senior lecturer at London School of Pharmacy (now UCL School of Pharmacy), UK, 2006
  • Dr. Helmut Legerlotz Fellow, University of Zurich, Institute of Organic Chemistry, Switzerland, 2002
  • Post-doctoral fellow, University of Utah, College of Pharmacy, USA, 1998-2001
  • PhD (Distinction) at ETH Zurich, Department of Pharmacy, Switzerland, 1997


Distinctions and Awards 

  • Waters Award for Excellence in Natural Products Innovation, 2016
  • Egon Stahl Silver Medal of Society for Medicinal Plant Research (GA), 2005
  • Pierre Fabre Prize of the Phytochemical Society of Europe (PSE), 2004
  • ETH-Zurich Medal, Distinction for PhD Thesis, 1997


Editorial Functions

  • Member of the Editorial Board of Marine Drugs
  • Member of the Advisory Editorial Board of Planta Medica
  • Member of the Editorial Board of Phytochemistry Letters

Functions in Learned Natural Product Societies

  • Member of the Advisory Board of Society for Medicinal Plant and Natural Product Research (GA). 2009 - 2015
  • Member of the Permanent Committee of Young Researchers Workshop,
  • Society for Medicinal Plant and Natural Product Research (GA). 2009 - 2015
  • Membership secretary of the Phytochemical Society of Europe (PSE). 2008 - 2013


Selected Publications

Tasdemir, D. Scarpato, S., Utermann-Thüsing, C., Jensen, T., Blümel, M., Wenzel-Storjohann, A., Welsch., C., Echelmeyer, V.A. Epiphytic and endophytic microbiome of the seagrass Zostera marina: Do they contribute to pathogen reduction in seawater? Science of the Total Environment, 2024, 908, 168422.

Vitale, G.A., January, G.G., Oppong-Danquah, E., Della Sala, G., Esposito, F.P., Tasdemir, D., de Pascale, D. A metabologenomics approach to unlock the metabolome of the novel Antarctic deep-sea isolate Lacinutrix shetlandiensis sp. nov. WUR7. PNAS Nexus, 2023, 2 (7): pgad221, doi: 10.1093/pnasnexus/pgad22.

Oppong-Danquah, E., Blümel, M., Scarpato, S., Mangoni, A., Tasdemir, D. Induction of isochromanones by co-cultivation of the marine fungus Cosmospora sp. and the phytopathogen Magnaporthe oryzae. International Journal of Molecular Sciences, 2022, 23(2), 782, doi: 10.3390/ijms23020782.

Sigwart, J., Blasiak, R., Jaspars, M., Jouffray J.-B., Tasdemir D. Unlocking the potential of marine biodiscovery. Natural Product Reports, 2021, 38, 1235-1242, doi: 10.1039/d0np00067a.

Li, F., Pandey, P., Janussen D., Chittiboyina A.G., Ferreira D., Tasdemir, D. Tridiscorhabdin and didiscorhabdin, the first discorhabdin oligomers linked with a direct C-N bridge from the Antarctic deep-sea sponge, Latrunculia biformis. Journal of Natural Products, 2020, 83, 706-713. doi: 10.1021/acs.jnatprod.0c00023

Parrot D., Blümel M., Utermann, C., Chianese G., Krause S., Kovalev, A., Gorb, S.N., Tasdemir, D. Mapping the surface microbiome and metabolome of brown seaweed Fucus vesiculosus by amplicon sequencing, integrated metabolomics and imaging techniquesScientific Reports, 2019, 9, 1061. doi: 10.1038/s41598-018-37914-8.

Papazian, S., Parrot, D., Buryskova, B., Weinberger, F., Tasdemir, D. Surface chemical defence of the eelgrass Zostera marina against microbial foulers. Scientific Reports 2019, 9, 3323. doi: 10.1038/s41598-019-39212-3.

Heavisides, E., Rouger, C., Reichel, A., Ulrich, C., Wenzel-Storjohann, A., Sebens, S., Tasdemir, D. Seasonal variations in the metabolome and bioactivity profile of Fucus vesiculosus extracted by an optimised pressurised liquid extraction protocol. Marine Drugs, 2018, 16, 503. doi: 10.3390/md16120503.

Chianese G., Esposito, F.P., Parrot D., Ingham, C., de Pascale, D., Tasdemir, D. Linear aminolipids with moderate antimicrobial activity from the Antarctic Gram-negative bacterium Aequorivita sp., Marine Drugs, 2018, 16, 187, doi: 10.3390/md16060187.

Utermann C., Parrot D., Breusing C., Stuckas H., Staufenberger T., Blümel M., Labes A., Tasdemir D. Combined genotyping, microbial diversity and metabolite profiling studies on farmed Mytilus spp. from Kiel Fjord. Scientific Reports 2018, 8:7983, doi: 10.1038/s41598-018-26177-y.

Parrot, D., Papazian, S., Foil, D., Tasdemir D. Imaging the unimaginable: Desorption Electrospray Ionization - Imaging Mass Spectrometry (DESI-IMS) in natural product researchPlanta Medica, 2018, doi: 10.1055/s-0044-100188.

Smyrniotopoulos, V., Merten, C., Kaiser, M., Tasdemir, D. Bifurcatriol, an antiprotozoal acyclic diterpene from the brown alga Bifurcaria bifurcataMarine Drugs, 2017, 15, 245, doi:10.3390/md15080245.

Silber, J., Kramer, A., Labes, A., Tasdemir, D. From discovery to production: biotechnology of marine fungi for the production of new antibiotics. Marine Drugs, 2016, 14(7), 137. doi:10.3390/md14070137.

Merten, C., Smyrniotopoulos, V., Tasdemir, D. Assignment of absolute configurations of highly flexible linear diterpenes from the brown alga Bifurcaria bifurcata by VCD spectroscopy. Chemical Communications, 2015, 51, 16217-16220.

Fernández, A., Grienke, U., Soler-Vila, A., Guihéneuf, F., Stengel, D., Tasdemir, D. Seasonal and geographical variations in the biochemical composition of the blue mussel (Mytilus edulis L.) from Ireland. Food Chemistry, 2015, 177, 43-52.

Grienke, U., Silke, J., Tasdemir, D. Bioactive compounds from marine mussels and their effects on human health. Food Chemistry, 2014, 142, 48-60.

Chianese, G., Fattorusso, E., Scala, F., Teta, R., Calcinai, B., Bavestrello, G., Dien, H.A., Kaiser, M., Tasdemir, D., Taglialatela-Scafati, O. Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin. Organic & Biomolecular Chemistry, 2012, 10, 7197-7207.

Fitzgerald, C., Gallagher, E., Tasdemir, D., Hayes, M. Heart health peptides from macroalgae and their potential use in functional foods. Journal of Agricultural and Food Chemistry, 2011, 59, 6829-6836.

Sertan, A.A., Predicala, R.Z., Bernardo, E.B., Neilan, B.A., Elardo, S.P., Mangalindan, G.C., Tasdemir, D., Ireland, C.M., Barraquio, W.L., Concepcion, G.P. Pseudovibrio denitrificans strain Z143-1, a heptyl prodigiosin-producing bacterium isolated from a Philippine tunicate. FEMS Microbiology Letters, 2007, 277, 188-196.

Tasdemir, D., Topaloglu, B., Perozzo, R., Brun, R., O’Neill, R., Carballeira, N.M., Zhang, X., Tonge, P.J., Linden, A., Rüedi, P. Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli. Bioorganic & Medicinal Chemistry, 2007, 15, 6834-6845.

Davis, R.A., Mangalindan, G.C., Bojo, Z.P., Antemano, R.R., Rodriguez, N.O., Concepción, G.P., Samson, S.C., de Guzman, D., Cruz, L.J., Tasdemir, D., Harper, M.K., Feng, X., Carter, G.T., Ireland C.M. Microcionamides A and B, bioactive peptides from the Philippine sponge Clathria (Thalysias) abietinaJournal of Organic Chemistry, 2004, 69, 4170-4176.

Marshall, K.M., Matsumoto, S.S., Holden, J.A., Concepcion, G.P., Tasdemir, D., Ireland, C.M., Barrows, L.R. The anti-neoplastic and novel topoisomerase II mediated cytotoxicity of Neoamphimedine, a marine pyridoacridine. Biochemical Pharmacology, 2003, 66, 447-458.

Tasdemir, D., Mallon, R., Greenstein, M., Feldberg, L.R., Kim, S.C., Collins, K., Wojciechowicz, D., Mangalindan, G.C., Concepción, G.P., Harper, M.K., Ireland, C.M. Aldisine alkaloids from the Philippine sponge Stylissa massa are Potent Inhibitors of Mitogen-Activated Protein Kinase Kinase-1 (MEK-1). Journal of Medicinal Chemistry, 2002, 45, 529-532.

Tasdemir, D., Marshall, K.M., Mangalindan, G.C., Concepción, G.P., Barrows, L.R., Harper, M.K., Ireland, C.M. Deoxyamphimedine, a new pyridoacridine alkaloid from two tropical Xestospongia sponges. Journal of Organic Chemistry, 2001, 66, 3246-3248.