Natural products from bacteria (2008-2013)

Lang, G., Kalvelage, T., Peters, A., Wiese, J. and Imhoff, J.F.: Linear and cyclic peptides from the entomopathogenic bacterium Xenorhabdus nematophilus. J. Nat. Prod. 71, 1074-1077 (2008).

Hohmann, C., Schneider, K., Bruntner, C.G., Brown, R., Jones, A.L., Goodfellow, M., Krämer, M., Imhoff, J.F., Nicholson, G., Fiedler, H.-P., Süssmuth, R.D.: Albidopyrone, a new alpha-pyrone containing metabolite from marine-derived Streptomyces sp. NTK 227. J. Antibiotics 62, 75-79 (2009).

Hohmann, C., Schneider, K., Bruntner, C., Irran, E., Nicholson, G., Bull, A.T., Jones, A.L., Brown, R., Stach, J.E.M., Goodfellow, M., Beil, W., Krämer, M., Imhoff, J.F., Süssmuth, R.D., Fiedler, H.-P.: Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep sea strain Streptomyces sp. NTK 937. J. Antibiotics 62, 99-104 (2009).

Helaly, S., Schneider, J., Nachtigall, J., Vikineswary, S., Tan, G.Y.A., Zinecker, H., Imhoff, J.F., Süssmuth, R.D. & Fiedler, H.P.: Gombapyrones, new α-pyrone metabolites produced by Streptomyces griseoruber Acta 3662. J. Antibiotics 62, 445-452 (2009).

Schulz, D., Nachtigall, J., Riedlinger, J., Schneider, K., Poralla, K., Imhoff, J.F., Beil, W., Nicholson, G., Fiedler H.-P. & Süssmuth, R.: Piceamycin and its N-acetylcysteine adduct are produced by Streptomyces sp. GB 4-2. J. Antibiotics 62, 513-518 (2009).

Schneemann, I., Ohlendorf, B., Zinecker, H., Nagel, K., Wiese J. & Imhoff, J.F.: Nocapyrones A - D, γ-Pyrones from a marine Nocardiopsis strain isolated from the marine sponge Halichondria panicea. J. Nat. Prod. 73, 1444-1447 (2010).

Schneemann, I., Kajahn, I., Ohlendorf, B., Zinecker, H., Erhard, A., Nagel, K., Wiese, J. & Imhoff, J.F.: Mayamycin, a cytotoxic polyketide from a Streptomyces strain isolated from the marine sponge Halichondria panicea. J. Nat. Prod. 73, 1309-1312 (2010).

Paululat, T., Kulik, A., Hausmann, H., Karagouni, A.D., Zinecker, H., Imhoff, J.F. & Fiedler, H.-P.: Grecocyclines, new Angucyclines from Streptomyces sp. Acta 1362. Eur. J. Org. Chem. 12, 2344-2350 (2010).

Nachtigall, J., Schneider, K., Nicholson, G., Goodfellow, M., Zinecker, H., Imhoff, J.F., Süssmuth, R.D. & Fiedler, H.-P.: Two new aurachins from Rhodococcus sp. Acta 2259. J. Antibiotics 63, 567-569 (2010).

Gärtner, A., Ohlendorf, B., Schulz, D., Zinecker, H., Wiese, J., Imhoff, J. F.: Levantilides A and B, 20-membered macrolides from a Micromonospora strain isolated from the Mediterranean deep-sea sediment. Marine Drugs 9, 98-108 (2011).

Imhoff, J.F., Labes, A. & Wiese. J.: Biomining the microbial treasures of the ocean: new natural products. Biotechnol Advances 29, 468-482 (2011).

Brötz, E., Kulik, A., Vikineswary, S., Lim, C.T, Tan, G.Y.A., Zinecker, H., Imhoff, J.F., Paululat, T. & Fiedler, H.-P.: Phenelfamycins G and H, new elfamycin-type antibiotics produced by Streptomyces albospinus Acta 3619. J. Antibiotics 64, 257-266 (2011)

Schneemann, I., Wiese, J., Kunz, A. & Imhoff, J.F.: Genetic approach for the fast discovery of phenazine producing marine Actinobacteria. Marine Drugs 9, 772-789 (2011).

Nachtigall, J., Schneider, K., Bruntner, C., Bull, A.T., Goodfellow, M., Zinecker, H., Imhoff, J. F., Nicholson, G., Irran, E., Süssmuth, R. D. & Fiedler H.-P.: Benzoxacystol, a benzoxazine-type enzyme inhibitor from the deep-sea strain Streptomyces sp. NTK 935. J. Antibiotics 64, 453-457 (2011). 

Kim, B.-Y., Willbold, S., Kulik, A., Helaly, S.E., Zinecker, H., Wiese, J., Imhoff, J.F., Goodfellow, M., Süssmuth, R. & Fiedler, H.-P.: Elaiomycins B and C, novel alkylhydrazides produced by Streptomyces sp. BK 190. J. Antibiotics 64, 595-597 (2011).

Ohlendorf, B., Simon, S., Wiese, J. & Imhoff, J.F.: Szentiamide, an N-formylated cyclic depsipeptide from Xenorhabdus szentirmaii DSM 16338T. Nat. Prod. Comm. 6, 1247-1250 (2011).

Schulz, D., Beese, P., Ohlendorf, B., Erhardt, A., Zinecker, H., Dorador, C. & Imhoff, J.F.: Abenquins, aminoquinone derivatives produced by Streptomyces sp. strain DB634. J. Antibiotics 64, 763-768 (2011).

Nachtigall, J., Kulik, A., Bull, A.T., Goodfellow, M., Asenjo, J.A., Maier, A., Wiese, J., Imhoff, J.F., Süssmuth, R.D. & Fiedler, H.-P.: Atacamycins A-C, 22-membered antitumor macrolactones from Streptomyces sp. C38. J. Antibiotics 64, 775-780 (2011).

Helaly, S.E., Kulik, A., Zinecker, H., Ramachandaran, K., Tan, A., Imhoff, J.F., Süssmuth, R.D., Fiedler, H.-P., Vikineswary, S.: Langkolide, a 32-membered Macrolactone Antibiotic produced by Streptomyces sp. Acta 3062. J. Nat. Prod. 75, 1018- 1024 (2012).

Schulz, D., Nachtigall, J., Geisen, U., Kalthoff, H., Imhoff, J.F., Fiedler H.-P. & Süssmuth, R.: Silvalactam, a 24-membered macrolactam antibiotic produced by Streptomyces sp. Tü 6392. J. Antibiotics 65, 369-372 (2012). 

Ohlendorf, B., Schulz, D., Erhard, A., Nagel, N. & Imhoff, J.F.: Geranylphenazinediol, an acetylcholinesterase inhibitor produced by a Streptomyces species. J. Nat. Prod. 75, 1400-1404 (2012). 

Ohlendorf, B., Schulz, D., Beese, P., Erhard, A., Schmaljohann, R. & Imhoff, J.F.: Diacidene, a polyene dicarboxylic acid from a Micromonospora isolate from the German Wadden Sea. Z. Naturforsch. 67c, 445-450 (2012).

Manderscheid, N., Helaly, S.E., Kulik, A., Wiese, J., Imhoff, J.F., Fiedler, H.-P. & Süssmuth, R.D.: Elaiomycins K and L, new azoxy antibiotics from Streptomyces sp. Tü 6399. J. Antibiotics 66, 85-88 (2013).

Kalyon, B., Tan, G-Y.A., Pinto, J.M., Foo, C-Y., Wiese, J., Imhoff, J.F., Süssmuth, R.D., Sabaratnam, V. & Fiedler, H.-P.: Langkocyclines, novel angucycline antibiotics from Streptomyces sp. Acta 3034. J. Antibiotics 66, 609-616 (2013).

Helaly, S.E., Goodfellow, M., Zinecker, H., Imhoff, J.F., Süssmuth, R.D. & Fiedler, H.-P.: Warkmycin, a novel angucycline antibiotic produced by Streptomyces sp. Acta 2930. J. Antibiotics 66, 669-674 (2013).

Pesic, A., Baumann, H.I., Kleinschmidt, K., Ensle, P., Wiese, J., Süssmuth, R.D., Imhoff, J.F.: Champacyclin, a cyclic octapeptide from Streptomyces strain C42 isolated from the Baltic Sea. Marine Drugs 11, 4834-4857 (2013).

Jetter, P., Steinert, C., Knauer, M., Zhang, G.L., Bruhn, T., Wiese J., Imhoff, J.F., Fiedler, H.-P., Bringmann, G.: New bhimamycins from Streptomyces sp. AK 671. J. Antibiotics 66, 719-726 (2013).